Medical Express

ISSN (print): 2318-8111

ISSN (online): 2358-0429

Author's Articles

1 result(s) for: Rafael C Freire

Unveiling the specific role of psychological and cardiorespiratory variables in the therapeutic effect of an aerobic exercise training protocol for panic disorder

Aline Sardinha; Raphael Marques Gomes; Claudio Gil Soares de Araújo; Rafael C Freire; Marina Dyskant Mochcovitch; Andrea Camaz Deslandes; Antonio E Nardi

MEDICALEXPRESS 2018;5(0): - ORIGINAL RESEARCH

Abstract PDF

BACKGROUND: There is limited evidence regarding the use of exercise training in the treatment of panic disorder.
OBJECTIVE: To describe the role of psychological and cardiorespiratory variables in the therapeutic effect of a 12-week exercise training in panic disorder patients.
METHODS: Eleven symptomatic panic disorder patients completed 24 sessions, 2 sessions/week, 70%VO2max) aerobic exercise training in addition to regular pharmacological treatment. Assessment was performed at baseline, six and 12-week periods. Exercise training intensity was individualized according to maximal cardiopulmonary exercise testing data.
RESULTS: Patients who exercised in conjunction with pharmacotherapy obtained significant improvements in several variables. Exercise training produced a selective, rather than a general anxiolytic impact. An early (6-week) effect was observed in fear of physiological arousal, interoceptive conditioning and in the frequency and intensity of panic attacks. Smaller additional 12-week effects were found in health concerns and agoraphobic cognitions, with no significant impact in agoraphobia.
CONCLUSION: A 12-week aerobic exercise training protocol was well-tolerated and able to improve several psychological and cardiovascular indicators in most patients with panic disorders. Further studies are needed to identify the best training protocols and long-term effects of exercise, as well as interactions between cardiorespiratory and psychological variables in this context.



Keywords: Mental health, Anxiety sensitivity, Interoceptive exposure, Exercise, Cardiovascular risk.